Important Safety Information for Humalog
What is the most important information I should know about Humalog®?
- Do not change the insulin you use without talking to your healthcare provider. Doses
of oral antidiabetic medicines may also need to change if your insulin is changed.
- Test your blood sugar levels as your healthcare provider instructs.
- When used in a pump, do not mix Humalog with any other insulin or liquid.
Who should not take Humalog?
- Do not take Humalog if your blood sugar is too low (hypoglycemia) or if you are
allergic to insulin lispro or any of the ingredients in Humalog.
Before using Humalog, what should I tell my healthcare providers?
Tell your healthcare providers:
- About all of your medical conditions, including liver or kidney problems.
- If you are pregnant or breastfeeding.
- About all the medicines you take, including prescription and non-prescription medicines,
vitamins, and herbal supplements.
How should I use Humalog?
- Humalog is a rapid-acting insulin. Take Humalog within fifteen minutes before eating
or right after eating a meal.
- Always make sure you receive the correct type of Humalog from the pharmacy.
- Do not use Humalog if it is cloudy, colored, or has solid particles or clumps in
it.
- Do not mix Humalog with insulin other than NPH when using a syringe. Do not mix
or dilute Humalog when used in a pump.
- Inject Humalog under your skin (subcutaneously). Never inject into a vein or muscle.
Change (rotate) your injection site with each dose. Make sure you inject the correct
insulin and dose.
- Depending on the type of diabetes you have, you may need to take Humalog with a
longer-acting insulin or with oral antidiabetic medicines.
- If you forget to take your dose of Humalog, your blood sugar may go too high (hyperglycemia),
which can lead to serious problems like loss of consciousness (passing out), coma,
or even death.
- Your insulin dose may need to change because of illness, stress, other medicines
you take, change in diet, or change in physical activity or exercise.
What are the possible side effects of Humalog?
- Low blood sugar is the most common side effect. There are many causes of low blood
sugar, including taking too much Humalog. It is important to treat it quickly. You
can treat mild to moderate low blood sugar by drinking or eating a quick source
of sugar right away. If severe, low blood sugar can cause unconsciousness (passing
out), seizures, and death. Symptoms may be different for each person. Be sure to
talk to your healthcare provider about low blood sugar symptoms and treatment.
- Severe life-threatening allergic reactions (whole-body reactions) can happen. Get
medical help right away if you develop a rash over your whole body, have trouble
breathing, have a fast heartbeat, or are sweating.
- Reactions at the injection site (local allergic reaction) such as redness, swelling,
and itching can happen. If you keep having skin reactions or they are serious, talk
to your healthcare provider. Do not inject insulin into a skin area that is red,
swollen, or itchy.
- Skin may thicken or pit at the injection site (lipodystrophy). Do not inject insulin
into skin with these types of changes.
- Other side effects include swelling of your hands and feet, low potassium in your
blood (hypokalemia), and weight gain.
- These are not all of the possible side effects. Ask your healthcare providers for
more information or for medical advice about side effects.
You are encouraged to report negative side effects of Prescription drugs to the
FDA. Visit
or call
1-800-FDA-1088.
How should I store Humalog?
- Unopened Humalog should be stored in a refrigerator and can be used until the expiration
date on the carton or label.
- Humalog should be stored away from light and heat. Do not use insulin if it has
been frozen.
- Opened vials should be kept at room temperature or in a refrigerator. Opened cartridges
or prefilled pens should be kept at room temperature.
- Once opened, Humalog vials, prefilled pens, and cartridges should be thrown away
after 28 days.
Humalog is available by prescription only.
For additional information, talk to your healthcare providers and please click to
access
Full Prescribing Information and Patient Information.
Please see full user manual that accompanies the pen.
Humalog® is a registered trademark of Eli Lilly and Company and is
available by prescription only.
Humalog® KwikPen™ is a registered trademark of Eli
Lilly and Company and is available by prescription only.
HumaPen® LUXURA™ is a registered trademark of Eli
Lilly and Company. HumaPen® LUXURA™ HD is available
by prescription only.
D-Tron® and D-Tronplus® are registered trademarks
of Roche Diagnostics GmbH.
Other product names mentioned herein are the trademarks of their respective owners.
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Important Safety Information for Glucagon
What is the most important information I should know about glucagon?
- Glucagon should not be used if you have pheochromocytoma or if you are allergic
to glucagon.
- Make sure you tell your healthcare provider if you have been diagnosed with or have
been suspected of having an insulinoma as glucagon should be used cautiously in
this situation.
- You and anyone who may need to help you during an emergency should become familiar
with how to use glucagon before an emergency arises. Read the Information for the
User provided in the kit.
- Make sure that your relatives or close friends know that if you become unconscious,
medical assistance must always be sought. If you are unconscious, glucagon can be
given while awaiting medical assistance.
- Do not use the kit after the date stamped on the bottle label.
- If you have questions concerning the use of this product, consult a doctor, nurse
or pharmacist.
WARNING: YOU MAY BE IN A COMA FROM SEVERE HYPERGLYCEMIA (HIGH BLOOD
GLUCOSE) RATHER THAN HYPOGLYCEMIA. IN SUCH A CASE, YOU WILL NOT
RESPOND TO GLUCAGON AND REQUIRE IMMEDIATE MEDICAL ATTENTION.
Who should not use glucagon?
Glucagon should not be used if you have pheochromocytoma or if you are allergic
to glucagon.
What should I tell my doctor before taking glucagon?
Tell your doctor about all of your medical conditions and prescription and over-the-counter
drugs. Tell your doctor if you have been diagnosed with or have been suspected of
having pheochromocytoma or an insulinoma.
How should I use glucagon?
- Act quickly. Prolonged unconsciousness may be harmful.
- Make sure your family and friends know to turn you on your side to prevent choking
if you are unconscious.
- The contents of the syringe are inactive and must be mixed with the glucagon in
the accompanying bottle immediately before giving injection. Do not prepare Glucagon
for Injection until you are ready to use it.
- Glucagon should not be used unless the solution is clear and of a water-like consistency.
- The usual adult dose is 1 mg (1 unit). For children weighing less than 44 lb (20
kg), give 1/2 adult dose
(0.5 mg).
For children, withdraw 1/2 of the solution from the bottle (0.5 mg mark on syringe).
Discard unused portion.
- You should eat as soon as you awaken and are able to swallow. Inform a doctor or
emergency services immediately.
What is some important Information I should know about Low Blood Sugar (Hypoglycemia)?
- Early symptoms of low blood sugar include: sweating, drowsiness, dizziness, sleep
disturbances, palpitation, anxiety, tremor, blurred vision, hunger, slurred speech,
restlessness, depressed mood, tingling in the hands, feet, lips, or tongue, irritability,
lightheadedness, abnormal behavior, inability to concentrate, unsteady movement,
headache, and personality changes. These symptoms may be different for each person
and can happen suddenly.
- If your low blood sugar is not treated, you may progress to severe low blood sugar
that can include: disorientation, seizures, unconsciousness, and death.
- Low blood sugar symptoms should be treated with a quick source of sugar which should
always be carried with you. If you do not improve or you are unable to take a quick
source of sugar, you should be treated with glucagon or with intravenous glucose
at a medical facility.
What are the possible side effects of glucagon?
- Severe side effects are very rare, although nausea and vomiting may occur occasionally.
- A few people may be allergic to glucagon or to one of the inactive ingredients in
glucagon, or may experience rapid heart beat for a short while.
- If you experience any other reactions which are likely to have been caused by glucagon,
please contact your doctor.
You are encouraged to report negative side effects of Prescription drugs to the
FDA. Visit
or call
1-800-FDA-1088.
How should I store glucagon?
- Before dissolving glucagon with diluting solution, store the kit at controlled room
temperature between 20° to 25°C (68° to 77°F).
- After dissolving glucagon with diluting solution, use immediately. Discard
any unused portion. Glucagon should be clear and of a water-like consistency
at time of use.
For more safety information, please click to access Information for the User and Information for the Physician.
The glucagon design is a trademark of Eli Lilly and Company. Glucagon is available
by prescription only.
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